Correlation of hyperprolactinemia, Subclinical hypothyroidism with Polycystic Ovary Syndrome and infertility

Background: Polycystic ovarian syndrome (PCOS) is a hyperandrogenic condition characterized by polycystic morphology and chronic oligo-anovulation. When it combines with hypothyroidism hyperprolactinemia, this can have severe consequences, may even lead to infertility.
 Case Presentation: This case study illustrates the complexity of PCOS significance multidisciplinary approach its diagnosis therapy. The patient 24-year-old non diabetic nonsmoker female who has been attempting conceive for seven years. presented hospital irregular menstrual cycles desire become pregnant. had previously unsuccessfully treated Clomid letrozole. patient's BMI was determined be 23. 3 pelvic scan indicated PCO ovaries. Laboratory results revealed hyperprolactinemia (53 ng/ml) subclinical (TSH 12.6 uIU/ml, T4 0.54 ng/dL- TPO antibodies:187 IU/mL, Anti thyroglobulin antibodies 235 IU/mL), but pituitary gland MRI normal. Thyroid US features going Hashimoto thyroiditis. symptoms were initially managed metformin Duphaston, then Cabergoline introduced address hyperprolactinemia. became pregnant shortly following medication. Prenatal screenings elevated fasting glucose levels gestational diabetes. blood sugar controlled Metformin, she later required multiple insulin doses maintain control. scheduled induction labor at 38 weeks, lower segment emergency cesarean surgery performed due fetal distress.
 Conclusion: Regular monitoring management both related conditions such as are crucial ensure best outcome patient. Additionally, we suggest treat having hyperprolactinemia.
 Keywords: syndrome, hypothyroidism,